Journal of Craniovertebral Junction and Spine

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 6  |  Issue : 3  |  Page : 120--124

Prediction of the efficacy of surgical intervention in patients with cervical myelopathy by using diffusion tensor 3T-magnetic resonance imaging parameters


Hironori Arima1, Shinichi Sakamoto2, Kentaro Naito1, Toru Yamagata3, Takehiro Uda1, Kenji Ohata1, Toshihiro Takami1 
1 Department of Neurosurgery, Osaka City University, Graduate School of Medicine, Osaka, Japan
2 Department of Diagnostic and Interventional Radiology, Osaka City University, Graduate School of Medicine, Osaka, Japan
3 Department of Neurosurgery, Osaka City General Hospital, Osaka, Japan

Correspondence Address:
Dr. Toshihiro Takami
Department of Neurosurgery, Osaka City University, Graduate School of Medicine, Osaka 545-8585
Japan

Background: The clinical significance of diffusion tensor (DT) magnetic resonance imaging (MRI) parameters was analyzed to predict postoperative functional recovery in patients with cervical myelopathy. Materials and Methods: Sixteen patients with cervical myelopathy caused by cervical spondylosis, disk herniation or ossification of the posterior longitudinal ligament who underwent surgical intervention in our institute were enrolled in this retrospective study. There were 7 men and 9 women, with a mean age of 62.8 years. Clinical assessment was done before surgery and at least 3 months after surgery. All patients underwent whole-body 3.0-Tesla MRI before surgery. DT images (DTIs) were obtained using a single-shot fast spin-echo-based sequence. Mean values of mean diffusivity (MD) and fractional anisotropy (FA) at 6 disk levels of the cervical spine were measured using manual setting of regions of interest. The MD and FA values at the most compressed part were analyzed. Absolute MD and FA values at the most compressed spinal level in patients were transformed into the normalized values with a z-score analysis. Results: MD-z may decrease with the severity of cervical myelopathy. Receiver operating characteristic analysis of MD-z and FA-z suggested that both MD-z and FA-z have clinical validity for predicting the efficacy of surgical intervention, but MD-z was considered to be the most appropriate value to predict the efficacy of surgery. Conclusions: DTIs may be a promising modality to predict functional recovery after surgery. MD changes may reflect spinal cord condition and its reversibility.


How to cite this article:
Arima H, Sakamoto S, Naito K, Yamagata T, Uda T, Ohata K, Takami T. Prediction of the efficacy of surgical intervention in patients with cervical myelopathy by using diffusion tensor 3T-magnetic resonance imaging parameters.J Craniovert Jun Spine 2015;6:120-124


How to cite this URL:
Arima H, Sakamoto S, Naito K, Yamagata T, Uda T, Ohata K, Takami T. Prediction of the efficacy of surgical intervention in patients with cervical myelopathy by using diffusion tensor 3T-magnetic resonance imaging parameters. J Craniovert Jun Spine [serial online] 2015 [cited 2022 May 19 ];6:120-124
Available from: https://www.jcvjs.com/article.asp?issn=0974-8237;year=2015;volume=6;issue=3;spage=120;epage=124;aulast=Arima;type=0