Journal of Craniovertebral Junction and Spine

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 7  |  Issue : 1  |  Page : 26--30

Diffusion tensor imaging of cervical spinal cord: A quantitative diagnostic tool in cervical spondylotic myelopathy


Zafer Orkun Toktas1, Bahattin Tanrikulu2, Orkun Koban3, Turker Kilic1, Deniz Konya1 
1 Department of Neurosurgery, School of Medicine, Bahcesehir University, Istanbul, Turkey
2 Department of Neurosurgery, Marmara University Research and Training Hospital, Istanbul, Turkey
3 Department of Neurosurgery, Marmara University Institute of Neurological Sciences, Istanbul, Turkey

Correspondence Address:
Zafer Orkun Toktas
Altaycesme Mah. Begonya Sok. No: 35/8 Gungoren Apartment, Maltepe - 34843, Istanbul
Turkey

Background: Diffusion tensor imaging (DTI) is a novel magnetic resonance imaging (MRI) technique potentially able to evaluate the microscopic structural organization of white matter fibers. Aim: This study aimed to compare fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values obtained by DTI in stenotic versus nonstenotic cervical spinal segments of patients with clinical and neurological evidence of cervical spondylotic myelopathy (CSM). Materials and Methods: This prospective study included 21 patients with CSM but without T2 changes on conventional MRI. Diffusion tensor (DT) images from the stenotic and nonstenotic segments of the subjects were obtained. FA and ADC values were estimated and compared with stenotic versus nonstenotic segments. Statistical Analysis: Paired t-test was used [Statistical Package for the Social Sciences (SPSS) 12.0]. Results: In the most stenotic segments, the mean FA value was significantly lower (0.4228 ± 0.1090 vs 0.6884 ± 0.0075, P < 0.001) and the mean ADC value was significantly higher (1.312 ± 0.2405 vs 0.9183 ± 0.1477, P < 0.001) when compared to nonstenotic segments. In addition, there was a negative correlation between FA and ADC values (r = 0.63, P = 0.002). Conclusions: DTI of the cervical spine seems to be a promising novel imaging modality in patients with CSM. Advances in Knowledge: DTI may offer increased diagnostic sensitivity as compared to standard MRI and enables earlier detection of the disease.


How to cite this article:
Toktas ZO, Tanrikulu B, Koban O, Kilic T, Konya D. Diffusion tensor imaging of cervical spinal cord: A quantitative diagnostic tool in cervical spondylotic myelopathy.J Craniovert Jun Spine 2016;7:26-30


How to cite this URL:
Toktas ZO, Tanrikulu B, Koban O, Kilic T, Konya D. Diffusion tensor imaging of cervical spinal cord: A quantitative diagnostic tool in cervical spondylotic myelopathy. J Craniovert Jun Spine [serial online] 2016 [cited 2022 May 26 ];7:26-30
Available from: https://www.jcvjs.com/article.asp?issn=0974-8237;year=2016;volume=7;issue=1;spage=26;epage=30;aulast=Toktas;type=0